Types of neurotransmitters. Types of neurotransmitter receptors. Neurotransmitter removal. Next lesson. Current timeTotal duration Google Classroom Facebook Twitter. Video transcript In this video, I wanna talk about how neurotransmitters are removed from the synapse. In other videos, we've talked about how action potentials travel down axons, and the information that's contained in action potentials, is really contained in the frequency of action potential firing, and the duration of a train of action potentials.
And when the action potential reaches the axon terminal, at the end of the axon, neurotransmitters are released into the synaptic cleft to bind to neurotransmitter recepters on the target cell. But if a neuron is firing action potentials very frequently, if there are large numbers of action potentials reaching the axon terminal, then the rate of neurotransmitter release into the synapse, may exceed the rate that neurotransmitter can just passively diffuse out of the synapse, so that diffusion is the first method by which neurotransmitter can be removed from a synapse, "Diffusion.
All nervous tissue outside of the central nervous system is part of what nervous system? How are the somatic and autonomic nervous systems similar? Which spinal segments have gray communicants? Which have white rami? What is the control center of the parasympathetic nervous system?
What is the center of control Which specific nerve receptors do Beta blockers block in the involuntary nervous system? There are three mechanisms for the removal of neurotransmitter: diffusion, degradation, and reuptake. Put another way, there are three ways to get rid of a neurotransmitter: wait for it to wander away, break it apart, or put it back in the vesicle. Diffusive processes affect all molecules, not just neurotransmitters: all else being equal, an ensemble of particles will, over time, decrease in its order.
Having more particles in the cleft than outside is a highly-ordered state, and so the particles move until the concentrations are equal. Due to the deep connection between disorder and information , we can think of this in another way: if there's more neurotransmitter in the synapse than outside, we can use the information provided by measuring neurotransmitter concentrations to determine our location.
When neurotransmitter has diffused away, that information disappears. Due to this ubiquity, diffusion affects neurotransmitter clearing at all synapses. For lipid-soluble neurotransmitters, like nitric oxide or the endocannabinoids, this is the only mechanism.
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